Sharon Rounds

Sharon Rounds, MD


Sharon Rounds MD is Principal Investigator of the CardioPulmonary Vascular Biology COBRE. She is also Chief of the Medical Service of the Providence VA Medical Center and Professor of Medicine and of Pathology and Laboratory Medicine at the Alpert Medical School of Brown University.

Dr. Rounds is a graduate of Wellesley College and of Tufts University School of Medicine. She trained in Internal Medicine at the University of California-San Francisco and did a Pulmonary/Critical Care fellowship at the University of Colorado. She began her career at Boston University School of Medicine, rising to Associate Professor of Medicine. She was appointed Associate Professor of Medicine at Brown Medical School in 1987 and Professor of Medicine in 1994. She served as Associate Dean of Medicine (Faculty Affairs) at Brown from 2001-2006.

Dr. Rounds has combined careers in clinical pulmonary/critical care medicine, teaching, and research on the pulmonary circulation. Basic science research interests include mechanisms of endothelial cell injury, effects of post-translational processing on small GTPase function, and effects of cigarette smoking on the pulmonary circulation. Her clinical research interests are pulmonary hypertension and Combined Pulmonary Fibrosis and Emphysema. An author of over 100 publications, she has been continuously supported by research grants from the NIH and/or VA since 1981. She was elected President of the American Thoracic Society in 2004-05. In recognition of her research achievements, Dr. Rounds was honored by the American Thoracic Society with a Scientific Achievement Award in 2009. Dr. Rounds has served as a member of many study sections for the NIH and other groups. She is currently a full member of the Respiratory Integrative Biology and Translational Research (RIBT) study section. She was PI for 12 years of the NHLBI-sponsored R25 grant to enhance diversity in health related research. She is co-PI of the T32 CardioPulmonary Research Training grant to train postdoctoral fellows.

Sharon Rounds has experience with both research and training and will use this background to fulfill the CardioPulmonary COBRE goal to enhance pulmonary and cardiovascular research in the State of Rhode Island.

COBRE Abstract

The overall purpose of the Administrative Core of the Cardiopulmonary Vascular Biology COBRE is to facilitate the research activities and career development of junior investigators who will go on to successfully apply for independent research support and become independent investigators. These objectives will be met by a comprehensive program of mentored individual research projects plus a career development curriculum. The objectives of the Administrative Core are:

  1. The Administrative Core will provide junior investigators with structures for mentoring, career development training, and administrative support.
  2. The Administrative Core will identify pilot investigators and will arrange for mentoring and career development support as they begin to develop research programs in the cardiopulmonary field.
  3. The Administrative Core will identify and add new junior investigators, as junior investigators become independent researchers.
  4. The Administrative Core will organize meetings of Mentoring, Executive,” Internal Advisory, and External Advisory Committees, weekly COBRE meetings, and the annual COBRE research symposium.
  5. The Administrative Core will manage consortium agreements with collaborating institutions.
  6. The Administrative Core will collect data for formative and summative evaluations of junior and pilot investigator progress.

The overall objective of the Cardiopulmonary Vascular Biology COBRE will be attained by a program of mentored research performed by talented junior investigators teamed with expert faculty mentors with extensive mentoring experience in productive and well-equipped laboratories. Progress toward independence of junior investigators will be monitored, using well-defined benchmarks of progress. The Administrative Core is critical to organization, scheduling, and facilitation and documentation of progress toward research independence.