Dr. Hongwei Yao was awarded a 12-month pilot project

Dr. Hongwei Yao was awarded a 12-month pilot project with the CPVB COBRE at the Ocean State Research Institute. Yao is currently appointed as an Associate Professor of Molecular Biology, Cell Biology & Biochemistry (Research) at Warren Alpert Medical School of Brown University. He has more than 10 years research experience studying the pathogenesis and potential pharmacological interventions in chronic lung diseases using in vitro in cells including endothelial cells, in vivo in animals and ex vivo in human peripheral tissues. His pilot project is entitled Metabolic Dysregulation in Pulmonary Endothelial Dysfunction during Hyperoxic Lung Injury. The long-term goal of this study is to determine the molecular mechanisms of hyperoxic lung injury during the development of Bronchopulmonary Dysplasia (BPD), as well as to identify the potential targets for therapeutic management for this disease.