Jillian McCullough, PhD Awarded 5 month Pilot Project

Jillian McCullough, PhD, was awarded a 5 month pilot project with the CardioPulmonary Vascular Biology COBRE at the Ocean State Research Institute. McCullough is completing her Postdoctoral training in Pulmonary Hypertension at the Vascular Research Laboratory at Alpert Medical School of Brown University and Providence VA Medical Center. Her pilot project is entitled “Peripheral Blood Flow and Exercise Intolerance in Pulmonary Arterial Hypertension.” The goal of the proposed research grant is to elucidate the role of the peripheral microvasculature as a potential contributor to exercise intolerance in pulmonary arterial hypertension.

Yang Zhou, PhD Awarded 5 month Pilot Project

Yang Zhou, PhD, was awarded a 5 month pilot project with the CardioPulmonary Vascular Biology COBRE at the Ocean State Research Institute. Zhou is currently an Assistant Professor (Research) in Molecular Microbiology and Immunology at Alpert Medical School of Brown University. His pilot project is entitled “ChI3L1and Pulmonary Hypertension Associated with Interstitial Lung Disease.” The experiments designed in this proposal will combine extensive experience in animal models of ILD and the expertise from investigators at CardioPulmonary Vascular Biology Center to obtain novel and important insights into the pathways leading to vascular remodeling responses in fibrotic lung diseases.

Brown Medicine Magazine Features CardioPulmonary Vascular Biology COBRE

Article on some of the research currently underway with CPVB COBRE investigators. Featuring Amanda Jamieson, Sharon Rounds, Elizabeth Harrington, Julie Newton, and Qing Lu.

Dr. Jun Feng Awarded Pilot Project with the CPVB COBRE

Dr. Jun Feng was awarded a 12 month pilot project with the CPVB COBRE at the Ocean State Research Institute. Feng is currently an Assistant Professor of Surgery (Research) at Warren Alpert Medical School Brown University and at Department of Surgery, Cardiovascular Research Center, Rhode Island Hospital. His pilot project is entitled Down Regulation of SKCa/IKCa Channels Contributes to Coronary Arterial Endothelial Dysfunction in Diabetic Patients. The aim of this pilot study is to advance understanding of coronary artery diseases, particularly macrovascular and microvascular diseases caused by metabolic syndrome, diabetes, and hypertension and to develop novel therapeutic strategies to effectively treat patients with metabolic syndrome, diabetes, hypertension and coronary artery diseases.

Dr. Olin Liang Awarded 12 Month Pilot Project with CPVB COBRE

Dr. Olin Liang was awarded a 12 month pilot project with the CPVB COBRE at the Ocean State Research Institute. Liang is currently a faculty member of the Center for Regenerative Medicine at Rhode Island Hospital and Warren Alpert Medical School of Brown University. His pilot project is entitled The Role of Endothelial to Hematopoietic Transition in Pulmonary Arterial Hypertension.

The aim of this pilot study is to determine whether a developmental process such as EHT may play a role in the pathogenesis of PAH, which may lead to identifying novel therapeutic targets.

Dr. Ruhul Abid Awarded American Heart Association Grant

The American Heart Association (AHA) has awarded three year Grant-in-Aid funding to CPVB Investigator, Dr. Ruhul Abid. His research entitled Mechanism for differential Effects of Short-term and Long-term Increase in ROS on Endothelium will begin July 1, 2014.

Abid is a primary investigator with the CPVB COBRE at the Ocean State Research Institute and is Associate Professor of Surgery at the Alpert Medical School of Brown University.

Dr. Amanda Jamieson Awarded 12 Month Pilot Project

Dr. Amanda Jamieson was awarded a 12 month pilot project with the CPVB COBRE at the Ocean State Research Institute. Jamieson began her tenure track appointment at Brown University July 1, 2013. Her pilot project is entitled Impact of influenza virus/L. pneumophila coinfection on lung endothelial cells. This project utilizes a unique model of co-infection for community acquired pneumonia and promises to enhance understanding of the role the pulmonary circulation in the pathogenesis of pneumonia.