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Peter Vitiello, PhD – Thioredoxin-dependent Redox Signaling in Lung Development

February 4 @ 3:00 pm - 4:00 pm

Fetal transitioning from the relatively hypoxic in utero environment to an oxygen-rich atmospheric environment represents a significant oxidative burden on the developing lung. Preterm lungs are already deficient in antioxidants and are poorly equipped to deal with the oxidative transition during parturition even before considering the adverse effects of therapeutic oxygen (hyperoxia) to treat poor respiratory function. This seminar will discuss oxygen-dependent redox signaling mechanisms in the context of lung epithelial developmental programming and hyperoxic injury.

About the speaker:
peter-vitielloDr. Vitiello is an Associate Professor of Pediatrics and Director of the Laboratory Research for Neonatal-Perinatal Medicine at the University of Oklahoma Health Sciences Center. His NIH-funded program uses molecular and cellular approaches to understand the molecular influence of environmental toxins, oxidative stress, and antioxidant enzymes on tissue development and disease pathogenesis. The Vitiello laboratory uses experimental models of oxidative diseases including bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), and Friedreich’s Ataxia (FRDA) to discover redox-dependent signaling mechanisms underlying pathogenesis.

Peter Vitiello, PhD
Associate Professor of Pediatrics
Director of Laboratory Research, Neonatal-Perinatal Medicine
Co-Director of the Center for Pregnancy & Newborn Research
The University of Oklahoma Health Sciences Center

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Details

Date:
February 4
Time:
3:00 pm - 4:00 pm
Event Category:

Venue

Zoom

Details

Date:
February 4
Time:
3:00 pm - 4:00 pm
Event Category:

Venue

Zoom