CardioPulmonary Vascular Biology Center for Biomedical Research Excellence (COBRE) 2022 Pilot Projects Program

The 2022 Pilot Projects Program will fund up to $75,000 projects for one-year research grants for eligible applicants. Indirect costs will not be provided to the applicants’ home institutions. Interested applicants are required to apply through the UFunds online portal no later than Wednesday, July 20, 2022 at 5pm ET.

Scientific Core Service Awards Voucher Program

The Cardiopulmonary Vascular Biology (CPVB) COBRE seeks applicants for Scientific Core Service Awards to foster your research, publications and grants. No award will be issued for more than $5,000.

Vouchers can only be awarded to investigators in IDeA states. The IDeA States are composed of the Commonwealth of Puerto Rico and the following 23 states: Alaska, Arkansas, Delaware, Hawaii, Idaho, Kansas, Kentucky, Louisiana, Maine, Mississippi, Montana, Nebraska, Nevada, New Hampshire, New Mexico, North Dakota, Oklahoma, Rhode Island, South Carolina, South Dakota, Vermont, West Virginia, and Wyoming.

Pilot Projects Program is Currently Closed

The Pilot Projects program is currently closed. Information about future pilot programs will be announced, please refer to our Twitter account for regular updates.

Pilot Projects Closed

The Pilot Projects Program is currently closed. The most recent application cycle closed in March 2020. Future requests for applications will be announced on

CardioPulmonary Vascular Biology Center for Biomedical Research Excellence (COBRE) 2020





Interested applicants are required to apply through the UFunds online portal no later than Monday, March 16, 2020 at 5pm ET. The Application must include the following:

  1. Contact and academic information as requested via the UFunds application page.
  2. Structured one-page overview of research aims, significance, and approach.
  3. References.
  4. NIH-formatted bio-sketch for each investigator and mentor.
  5. Letter from Department Chair(s) stating postdoctoral fellow or resident physician applicants will have a faculty appointment by June 1, 2020, if applicable (not required for current faculty).

A Brown University ID is required to access UFunds. Non-Brown faculty should email by February18, 2020 to request a Brown University ID to use for this application.

Funding Available

The 2020 Pilot Projects Program will fund two $50,000 projects for one-year research grants. Indirect costs will not be provided to the applicants’ home institutions.

Performance Period

The anticipated performance period is 6/1/2020 to 5/31/2021.

Available Services for Applicants

All applicants are strongly encouraged to schedule a consultation with Cell Isolation and Organ Function Core to enhance their responsiveness to this RFA. Applicants are encouraged to review available services on the CPVB CORE lab-request-form for any inquiries. Please contact or or

Proposal Submission Instructions

Proposals are due through UFunds no later than Monday, March 16, 2020 at 5pm ET. CPVB COBRE will not consider applications that are incomplete.


Applications should follow an abbreviated NIH format with minor modifications. This application requires the use of the most recent version of the PHS 398 Forms.

Font: Arial, Helvetica, Palatino Linotype or Georgia typeface and a font size of 11 points or larger must be used. A Symbol font may be used to insert Greek letters or special characters; the font size requirement still applies. A smaller font size may be used for figures, graphs, diagrams, charts, tables, figure legends, and footnotes, but this type must follow the font typeface requirement and be readily legible. Margins: Margins should be ½ inch


Address inquiries regarding the CPVB COBRE pilot projects program to Susan McNamara, program administrator, at SUSAN.MCNAMARA@VA.GOV OR 401-273-7100 EXT.2679

CardioPulmonary Vascular Biology Center

CardioPulmonary Vascular Biology Center for Biomedical Research Excellence (COBRE)

Call for Pilot Project Applications

The CardioPulmonary Vascular Biology (CPVB) COBRE has the goal of increasing the quantity and quality of cardiovascular and pulmonary research in Rhode Island. One means of attaining this goal is identification and nurturing of talented young investigators. Therefore, the CPVB COBRE announces the availability of two $50,000 pilot projects for research related to cardiovascular and pulmonary diseases. The goal of these pilot projects is to enable investigators to develop preliminary data that can be used to support successful applications for independent research funding in vascular biology. In addition, pilot project investigators are expected to participate in COBRE meetings and activities and in career development activities to enhance skills for academic and research success.

The CPVB COBRE includes a Cell/Organ Function Core to support investigator research.

Anticipated start date is June 1, 2019.

Eligibility: Faculty or senior post-doctoral fellows on the cusp of faculty appointment at a Rhode Island academic institution are eligible to apply. Individuals who have received external funding from an RO1, K99, R00 or equivalent are ineligible for pilot funding. Investigators must identify a mentor in a field related to the proposed research

Application process: Applications will follow abbreviated NIH format with minor modifications.
Use PHS Form 398.

Face page: should include investigator name, academic title, institution, address, title of project, and institutional grants management official.

Project Summary (page 2): One page summary of the proposal.

Budget: Itemize and include brief budget justification. Costs for equipment or renovation are not permitted. Direct costs only will be funded.

Bio sketch: A bio sketch for the PI and mentor should be provided.

Research Strategy Section: Limited to 6 single-spaced pages, excluding references. Follow NIH PHS Form 398 outline. The Research Plan should include the following:

  • Specific Aims: Describe the project goals for 1 year pilot project period. No more than ½ page recommended.
  • Significance: Include overall significance of the project, including relevance to goals of the CPVB COBRE, and plans for use of data from pilot project for subsequent independent funding.
  • Innovation: Include both conceptual and any technical innovation.
  • Approach: Preliminary data and research plan, including data analysis, anticipated results and alternative approaches. It is strongly recommended that use of the Core be proposed. Preliminary data is not required, but is encouraged.

References: Not included in 6 page limit.

Protection of Human Subjects/Vertebrate Animals: Per PHS Form 398. Provide IRB and/or IACUC approval(s). Provide Human Subjects education certification and Target/Planned Enrollment Table (if applicable). Provide 5 vertebrate animal points (if applicable).

Biosafety/Select Agents: Per PHS Form 398. Indicate Institutional Safety Committee approvals.

Additional Documentation: Applications must be accompanied by letters from Department Chair and/or supervisor documenting availability of protected time for research and plans for mentoring of the pilot investigator.

A letter from the mentor agreeing to advise on the conduct of the proposed research should be included with the application.

Review Process and Selection Criteria:
Applications will be reviewed by the CPVB Executive Committee for scientific merit including significance, investigators, innovation, and approach. In addition, reviews will include relevance to CPVB COBRE goals of enhancing research in Cardiovascular and/or Pulmonary diseases, potential for future independent funding, and institutional support. Preference will be given to applications relevant to vascular biology.

Funding is dependent upon review and approval by the CPVB COBRE External Advisory Committee and the NIGMS.

Address inquiries regarding CPVB COBRE Pilot Projects to the co-PIs, Sharon Rounds, MD or Elizabeth Harrington, PhD

Applications should be submitted as a single file pdf to

Important Dates:

Full Proposal Deadline: 5:00 pm April 1, 2019